Treatment outcomes of tuberculosis patients in a Directly Observed Treatment Short course (DOTS) Referral Centre in Delta State, Nigeria: a five-year review (2012 - 2016).

Introduction: The objective of this study is to observe the trend in treatment outcomes and identify determinants of treatment success among patients recruited into care through the DOTS strategy. Methodology: A retrospective record review of tuberculosis patients (2012-2016) was carried out at the Tuberculosis and Leprosy Referral Centre, Eku, Delta State, Nigeria. Results: Records of four hundred and twenty five (425) tuberculosis patients under DOTS were reviewed over five years. The highest number of cases under treatment, 102 (24.0%), was recorded in 2013. The mean age (SD) of patients was 37.3 (±16.5) years, majority of the patients were male (62.4%) and 18% had TB/HIV co-infection. Treatment outcomes of patients were cured (53.4%), completed (27.8%), died (6.8%), failed (2.4%), lost to follow up (4.9%), transferred out (1.2%) and not evaluated (3.5%). Over all, treatment success rate was 81.2% with a trend of 88.7% (2012), 87.3% (2013), 85.9% (2014), 65.0% (2015) and 65.8% (2016) respectively. Patient characteristics were not associated with treatment success. Conclusion: The treatment success rate was high and in line with the national recommendation of 80% and above. The trend showed a reduction in number of new cases enrolled into the DOTS programme, reduction in success rate with a concomitant increase in loss to follow up. There was no association between patient characteristics and TB treatment success. System strengthening on patient follow up, community health education and treatment adherence is recommended.

Knowledge, attitude and uptake of family planning services among women of reproductive age group attending outpatient clinic at a tertiary health institution in Edo State, Nigeria

Globally, family planning service is an essential element of reproductive health care and contributes immensely to the reduction of the worldwide burden of maternal and child morbidity and mortality. This study was designed to assess the knowledge, attitude and uptake of family planning services, among women of reproductive age group attending outpatient clinic at Irrua Specialist Teaching Hospital, Irrua, Nigeria. A cross-sectional study was carried out among women of reproductive age group attending outpatient clinics from December 2017 to January 2018. Respondents were selected using multi-stage sampling technique. Questionnaires were used for data collection. Data were analyzed using Statistical Package for Social Sciences SPSS version 17. A total of 191 (95.5%) women aged between 15 and 49 years were successfully interviewed during the study. Majority, 174/191 (91.1%) of the respondents had a good knowledge of family planning services; 125/174 (72.0%) had a positive attitude towards the use of various types of contraceptives and 29 (15.0%) were completely against the use of contraceptives. Majority of the respondents, 132 (69.0%) were not using any form of family planning. Condom was the most frequently used contraceptive method; where it accounts for 60.0% while sterilization contributes the least that is 22.0%. Major factors associated with the uptake of contraceptives include marital status (p=0.029) and the occupation of the respondents (p=0.010). Respondent's knowledge towards family planning was good but this did not translate to use. Also, over half of the respondents had positive attitude towards family planning. The uptake of family planning services was higher than the average for Edo State and for Nigeria. Common barriers to uptake included fear of side effects and for religious reasons. The state and local government should bridge the gap between awareness and uptake of contraception; by providing correct information to women of reproductive age to break down common barriers

Respiratory symptoms and ventilatory functions among quarry workers in Edo state, Nigeria.

INTRODUCTION: Workers in the quarry industries are exposed to hazards resulting from the inhalation of air borne particulates. The study determined the prevalence of respiratory symptoms and assessed ventilatory functions among quarry workers in Edo state, Nigeria. METHODS: Quarry workers (site workers and office workers) were interviewed using structured questionnaire. FEV1, FVC, FEV1/FVC and PEFR were measured using a KoKo Legend spirometer. RESULTS: A total of 113 quarry workers (76 exposure and 37 controls) were studied. The exposure group had significantly higher occurrence of chest tightness (35.5%) compared with 16.2% of the controls (p < 0.05). The occurrence of cough (23.7% versus 13.5%), sputum (21.1% versus 16.2%), and dyspnoea (7.9% versus 5.4%), were higher in exposure groups while wheeze (10.8% versus 10.5%) and nasal congestion (27.0% and 25.0%) were higher in the control groups. The mean (SD) FEV1, and FVC were significantly lower among the exposure compared with the control group; 2.77L (0.73) versus 3.14L (0.78), p < 0.05, and 3.48L (0.84) versus 3.89L (0.92), p < 0.05. In both groups, smokers had significantly lower mean (SD) FEV1, FVC and PEFR compared with non-smokers; 2.91L (0.77) versus 3.39L (0.69), p = 0.01, 3.61L (0.91) versus 4.26L (0.74), p < 0.05 and 6.56L (2.43) versus 7.98L (1.67), p < 0.05. CONCLUSION: Chronic exposure to quarry dust is associated with respiratory symptoms and reduced lung function indices among quarry workers. The enforcement of the use of PPEs and periodic evaluation the lung function status of quarry workers is advocated.